Management of Pigmented Villonodular Synovitis (PVNS): an Orthopedic Surgeon’s Perspective

Pigmented villonodular synovitis.

Pigmented villonodular synovitis.

Pigmented villonodular synovitis (PVS) is an uncommon, usually monoarticular disorder encountered mainly in adults. A boy and a girl, both 7 years old, were referred because of recurrent knee effusions. Both were medically treated for other rheumatic disorders for five years. PVS was diagnosed by arthroscopy and synovectomy was curative in both cases.

Successful treatment of relapsing Pigmented Villonodular Synovitis (PVNS) of the knee with radiosynoviorthesis

PVNS is a rare disorder characterised by benign proliferation of synovial tissue. The treatment is surgical but relapse rate is high (8% to 46%). We report a 13 years old girl with PVNS of the left knee diagnosed in February 2003. Three months after diagnosis she underwent surgical synovectomy. Two years later important swelling of left knee with pain and limitation of movement developed and MR...

Complete response to imatinib in relapsing pigmented villonodular synovitis/tenosynovial giant cell tumor (PVNS/TGCT).

letters to the editor Complete response to imatinib in relapsing pigmented villonodular synovitis/tenosynovial giant cell tumor (PVNS/TGCT) Pigmented villonodular synovitis (PVNS), also known as tenosynovial giant cell tumor (TGCT), is a rare pathological entity affecting the synovium in young adults [1, 2]. Initially considered as an inflammatory reactive process, recent observations have show...

Arthroscopic Management of Pigmented Villonodular Synovitis of the Knee Joint

INTRODUCTION Pigmented Villonodular Synovitis (PVNS) of knee joint is a rare disorder of Synovium. Hip and knee joint are commonly affected joints. The knee PVNS presents as a localized or diffuse form. Diagnosis if often delayed and permanent joint damage occurs with advanced disease. Ultrasound examination shows fluid collection and synovial hypertrophy. Magnetic resonance imaging helps in cl...